- A Case of Colchicine Intoxication Presenting as Acute Gastroenteritis
-
Ji-Yun Ahn, You-Dong Sohn, Hyuk-Sool Kwon, Hee-Chol Ahn
-
J Korean Soc Clin Toxicol. 2008;6(2):138-141. Published online December 31, 2008
-
-
-
 Abstract
 PDF
- A 47-year-old woman ingested about 12 mg of colchicine with suicidal intent. Colchicine, a highly poisonous alkaloid, is a commonly used treatment for gout, Bechet's disease, and familial Mediterranean fever. Despite the knowledge of its side effects, the risk of a significant overdose is under-appreciated. She suffered from acute multisystem toxicity, including gastrointestinal disorders, bone marrow suppression, alopecia, and probable pancreatitis, but she ultimately recovered with supportive therapy. We report a case of acute colchicine toxicity from a single overdose with a review of the literature.
- A one-year Follow-up Study of Patients Exposed to Chlorine Gas
-
Hyuk-Sool Kwon, You-Dong Sohn, Hee-Cheol Ahn, Ji-Yun Ahn
-
J Korean Soc Clin Toxicol. 2008;6(2):99-103. Published online December 31, 2008
-
-
-
Abstract
PDF
- Purpose: Chlorine gas is a common irritant that usually causes mild respiratory symptoms. One severe symptom, RADS (Reactive Airway Dysfunction Syndrome), is not well known to physicians. We analyzed the clinical features of chlorine gas exposure. Methods: We prospectively collected 25 cases of chlorine gas exposure near our emergency center on January 10th, 2007, and analyzed demographic data, event-to-ER interval, symptoms, and laboratory results based on medical records. Results: Only 2 patients out of 25 were admitted because of severe symptoms, the rest were discharged without complications. Sixty percent of them visited the ER within 12 h of exposure. The most common symptoms were chest discomfort (60%), headache (40%), nausea (40%), throat irritation (26%), and cough (32%). Two out of eight dyspnea cases showed abnormal pulmonary function, but only one case was diagnosed as RADS. Conclusion: Most symptoms after chlorine gas exposure can be treated conservatively. However, patients with chlorine exposure should be followed up long term for delayed complications.
- Nicotine Poisoning Using Nicotine Patches
-
You-Dong Sohn, Jae-Sung Lee, Gu-Hyun Kang, Jung-Tae Choi, Moo-Eob Ahn, Jeong-Youl Seo, Hee-Cheol Ahn
-
J Korean Soc Clin Toxicol. 2007;5(1):53-56. Published online June 30, 2007
-
-
-
Abstract
PDF
- Nicotine poisoning arising from the use of nicotine patches is rare. However, because nicotine patches are classified as an OTC drug, the risk of misuse or abuse is increasing. Nicotine poisoning using nicotine patches shows an unusual clinical presentation compared to that from oral ingestion of multiple doses of nicotine. We present a case of misused nicotine patches that cause a nicotine poisoning. A thirty-nine year-old healthy man visited the ER with complaints of an intermittent cramping abdominal pain with nausea and vomiting. Upon physical examination, there were no specific findings except increased bowel sounds, and the patient's initial laboratory findings were also unremarkable except for an increased bilirubin level. CT revealed a mild degree of fatty liver. The patient's symptoms did not improve any further with conservative management. During his ED stay, we meticulously took his history again, and we discovered that he had used nicotine patches for three days, six days before admission, and had misused the nicotine patches as NSAID patches. The patient's diagnosis of nicotine poisoning was confirmed by a urine cotinine level ten times the normal value. After a 12-hour stay in the ED, his symptoms disappeared without any specific management.
|
KSCT
Korean Society of Clinical Toxicology